Wednesday, July 10, 2024

A cancer moonshot progress report

The ideas and innovators shaping health care
Jul 10, 2024 View in browser
 
Future Pulse

By Erin Schumaker, Ruth Reader, Daniel Payne and Toni Odejimi

WASHINGTON WATCH

FILE - President Joe Biden speaks on the cancer moonshot initiative at the John F. Kennedy Library and Museum, Sept. 12, 2022, in Boston. Biden is requesting more than $2.8 billion in the federal budget proposal he's sending to Congress to help advance his cancer-fighting goals. That's according to White House officials, who shared details with The Associated Press before Biden unveils the proposal Thursday, March 9, 2023, in Philadelphia. (AP Photo/,   File)

Biden's set an audacious goal for his cancer moonshot. | Evan Vucci/AP Photo

The Biden administration kicks off a series of conversations with the president's "cancer cabinet" this afternoon.

The virtual conversations, which are part of the White House cancer moonshot initiative, include wide-ranging agencies and departments: the National Cancer Institute, the National Aeronautics and Space Administration, the Food and Drug Administration, the Centers for Disease Control and Prevention, the Advanced Research Projects Agency for Health and the Departments of Agriculture, Labor, Energy, Defense and Veterans Affairs.

The meetings are meant to highlight moonshot progress in key areas, including improving cancer prevention, increasing screening access, better understanding and addressing toxic exposure and environmental risks, strengthening support for patients and caregivers, and ensuring that cancer research, prevention and treatment innovations make it from the lab to patients.

YouTube will livestream the talks.

What we're listening for: Whether the moonshot is on track to hit the ambitious goal President Joe Biden set when he reignited the program: reducing the cancer death rate by half by 2045.

Big picture: While cancer is a bipartisan priority, it's not clear that Biden's program will endure if Republicans take power next year.

House Republicans have proposed slashing federal health research, with a House Appropriations subcommittee last month approving a funding bill that would cut ARPA-H's budget by $1 billion, though they also offered NCI a $651 million budget boost.

Still, deep research cuts aren't likely, given Democratic control of the Senate and the White House.

What's next? The first conversation, "Improving Cancer Outcomes: Bringing Research to Rural Communities," is at 2 p.m. today. Sessions run through July 17.

 

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WELCOME TO FUTURE PULSE

Brooklyn, N.Y.

Brooklyn, N.Y. | Erin Schumaker/POLITICO

This is where we explore the ideas and innovators shaping health care.

Who's laughing now? Large language models, apparently. ChatGPT wrote funnier jokes than humans and equally funny headlines compared with those in the satirical news site The Onion, a recent study published in the journal PLOS ONE found.

Share any thoughts, news, tips and feedback with Carmen Paun at cpaun@politico.com, Daniel Payne at dpayne@politico.com, Ruth Reader at rreader@politico.com, Erin Schumaker at eschumaker@politico.com, or Toni Odejimi at aodejimi@politico.com.

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THINK FAST

OpenAI CEO Sam Altman testifies before congress.

Altman's behind a new bot whose mission is self-improvement. | Francis Chung/POLITICO

ChatGPT progenitor Sam Altman and sleep-obsessed Huffington Post founder Arianna Huffington are teaming up to offer an artificial intelligence-backed health coach for the professional class.

Altman’s OpenAI Startup Fund and Huffington’s Thrive Global are behind the new company, Thrive AI Health, and its AI health coach. The tool will train on peer-reviewed studies and incorporate Thrive Global’s concept of healthy living.

Some examples of the bot’s wise guidance:

— Swap your third afternoon soda for water and lemon.

— Go on a 10-minute walk with your child after you pick them up from school.

— Start your wind-down routine at 10 p.m. since you have to get up at 6 a.m. tomorrow.

Why it matters: Studies have found AI tools have a friendly bedside manner. They’re always available and seem to be good at promoting healthy habits.

Even so: This kind of personalized advice — that accounts for schedule and health profile — will depend on people disclosing intimate personal details to Thrive Health AI. The company says it will have “robust privacy and security safeguards.”

While the Federal Trade Commission is cracking down on telehealth companies for improper sharing of personal health data, the U.S. doesn’t have a general privacy law.

 

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TECH MAZE

A photo taken on February 26, 2024 shows the logo of the Artificial Intelligence chat application on a smartphone screen (L) and and the letters AI on a laptop screen in Frankfurt am Main, western Germany. (Photo by Kirill KUDRYAVTSEV / AFP) (Photo by KIRILL KUDRYAVTSEV/AFP via Getty Images)

Researchers are finetuning AI systems on medical texts. | AFP via Getty Images

Advanced artificial intelligence is getting better at making sense of medical research, according to a new preprint study from the maker of one of the models.

How so? General-purpose bots like ChatGPT and Gemini didn’t perform well when asked 50 clinical questions, according to doctors who independently reviewed the responses. The answers were deemed “relevant and evidence-based” between 2 and 10 percent of the time.

But models specifically made for clinical knowledge, like ChatRWD by study sponsor Atropos Health, perform better. It uses a protocol that points to authoritative sources and produced evidence-based answers 58 percent of the time.

Even so: Many health AI tools rely on general-purpose models tweaked to ensure they draw on specific sources.

Why it matters: Doctors want to understand how AI tools work — and how trustworthy they are — before they use them to assist with clinical decision-making.

 

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Carmen Paun @carmenpaun

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Erin Schumaker @erinlschumaker

 

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