Notice of Special Interest (NOSI): Synthetic Biology for Biomedical Applications One of the great challenges in biomedical research is to be able to quantitatively predict, test, and harness the complex dynamics of biological systems. In contrast to the traditional genetic engineering approach, which usually focuses on individual genes and proteins, synthetic biology adopts a more systematic approach targeting entire pathways, networks, and whole organisms with quantitative control and modulation. Gaining new insights into the complex and dynamic biological pathways of designer cells and tissues and developing cell-based and cell-free diagnostics and therapies are at the frontiers of biomedical science. Enabling these de novo biological systems will require the ability to design and build complex pathways with endogenous or novel functions and with predictable and quantitative responses to endogenous or environmental signals. Achieving this paradigm will allow complex biological systems hypotheses to be tested and the development of novel therapeutic strategies and diagnostic capabilities. Learn more about NOT-EB-20-017. Notice of Special Interest (NOSI): Administrative Supplement for Providing Travel Support for Awardees to Attend the Annual NIH Synthetic Biology Consortium Meeting (Admin Supp) The National Institute of Biomedical Imaging and Bioengineering (NIBIB) announces the availability of Administrative Supplements to provide travel support for awardees of the Synthetic Biology for Biomedical Applications Notice to attend the annual NIH Synthetic Biology Consortium Meeting (eligible applicants are those who have received an award made in response to NOT-EB-20-017). | 
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