Charles River plans to manufacture a second-generation gene therapy for hemophilia A, ASC618.Good morning Wake-Up Watchlisters! While you're pounding those carrot turmeric shots you'll see stock futures dipped on Thursday. This was largely due to the Federal Reserve signaling willingness to accept a recession and more unemployment to contain inflation. Here's a look at the top-moving stocks this morning. Charles River (NYSE: CRL)Charles River is up 3.32% premarket after its recent deal with ASC Therapeutics. The company plans to manufacture a second-generation gene therapy for hemophilia A, ASC618. The program has gained clearance and other key regulatory designations in the United States and Europe. Keep an eye on Charles River going forward. Ecolab (NYSE: ECL)Ecolab is up 3% premarket. With record drought and heat expected on the west coast this summer, the water purification company is in a prime spot to benefit. The company also recently unveiled plans to build a wind farm on the western coast of Finland. This farm is expected to bring Ecolab's sustainable energy to 100% in Europe. Overall, Ecolab is looking strong. Now is the time to get in on water stocks as the world deals with climate change. We're currently positioned on another stock in this sector as part of our Trade of the Day portfolio. Click here to unlock this trade. Twitter (Nasdaq: TWTR)Twitter is up 2.50% premarket as Tesla CEO Elon Musk is expected to announce his intention to buy the company today. Musk, the world's richest person according to Forbes magazine, is trying to buy Twitter for $44 billion. Keep an eye on Twitter going forward. While we've seen Musk's Tesla company skyrocket in value over the last few years, there's another opportunity in the EV sector we want you to know about. Our friend Andy Snyder believes this 'ONE electric vehicle stock could help fund your entire retirement.' And right now you can still get in cheap. Click here to learn more about this EV stock. Opendoor Technologies (Nasdaq: OPEN)Opendoor is down 5.07% premarket as the latest Federal Reserve hikes impact the housing market. With homebuyers likely to see higher prices for homes, it's likely the company won't see as much demand. There's also a shortage of workers to build houses plus supply shortages for building material. Opendoor is looking volatile. How to Recognize Insider TradingWith so much shifting in the markets, it often pays to follow the money. Our Head Trading Fundamental Karim Rahemtulla shows you how to do that in this article. Click here to learn how to spot and profit from insider buying. Those are the top market movers today. Happy trading! The Wake-Up Watchlist Research Team | 
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