|  Today, the U.S. Food and Drug Administration approved Stelfonta (tigilanol tiglate injection) to treat dogs with non-metastatic, skin-based (cutaneous) mast cell tumors (MCTs). The FDA is also approving Stelfonta to treat non-metastatic MCTs located under the dog's skin (subcutaneous), in particular areas of a dog's leg. Stelfonta is injected directly into the MCT (intratumoral injection). Stelfonta works by activating a protein that spreads throughout the treated tumor, which disintegrates tumor cells. "This is the first approval for an intratumoral injection to treat non-metastatic mast cell tumors in dogs," said Steven M. Solomon, D.V.M., M.P.H., director of the FDA's Center for Veterinary Medicine. "This approval provides an additional treatment option to help treat local mast cell tumors on or under the skin in dogs." MCTs are the most common malignant skin tumor in dogs, and usually present as a lump on or under the skin. Full surgical removal of mast cell tumors can be difficult when tumors are located in certain areas, such as the leg. When mast cell tumors are not fully removed, the remaining malignant cells can start to... | | | |
No comments:
Post a Comment