03/17/2021 This Funding Opportunity Announcement (FOA) encourages applications from institutions and organizations proposing original research aimed at the characterization of the function of neoepitopes and neoantigens in type 1 diabetes. This includes the function that post-translational modifications might have in the humoral and cell mediated autoimmune responses and overall in the etiology and pathophysiology of type 1 diabetes. Proposals that include the discovery of neoantigens or neoepitopes are within the scope of this solicitation, but should propose a plan for integrating these discoveries with the present knowledge on established epitopes and antigens (e.g. autoantibodies for insulin, GAD65, IA-2, and ZnT8). In the long-term the goals of this initiative are to facilitate the development of better tools to monitor disease progression and treatment, and potentially to facilitate the development of personalized therapeutics. 03/15/2021 The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this OBSSR R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on Courses for Skills Development.
OBSSR and participating Institutes and Centers will support educational activities that develop cross-cutting methodologies and analytics that are needed to more rapidly advance behavioral and social sciences research (BSSR) and are not already well addressed by existing educational programs widely available to the research community. Methodological domains of focus include but are not limited to innovative data collection methodologies and analytic techniques, analysis and linking of big data, or needed but underused designs to advance research across the translational spectrum. Priority will be given to courses that address an important and cross-cutting educational need, that fill a gap in the field not already well addressed by other opportunities and that include a plan for increased reach and sustainability of the training both during and beyond the funding period. Over the period of support, it is expected that the course will be refined, improved, and sufficiently developed and implemented to extend beyond in-person attendance, and beyond the end of the project period (e.g. videos, slides, course materials).
Pamela L. Thornton, Ph.D.; David E. Saslowsky, Ph.D.; Victoria Spruance, Ph.D. | RFA-OD-21-005
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